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p53 17-26
CAS No. 488118-64-5
p53 17-26( —— )
Catalog No. M30492 CAS No. 488118-64-5
This peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Namep53 17-26
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NoteResearch use only, not for human use.
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Brief DescriptionThis peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2.
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DescriptionThis peptide is amino acids 17 to 26 fragment of p53, the Mdm-2 binding domain of p53 known also as p53N. This sequence contains all of the residues that contact the binding domain of Mdm-2.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetMDM2-p53
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number488118-64-5
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Formula Weight1251.43
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Molecular FormulaC60H90N12O17
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameSequence:{Glu}{Thr}{Phe}{Ser}{Asp}{Leu}{Trp}{Lys}{Leu}{Leu}
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
Michl J, et al. PNC-28, a p53-derived peptide that is cytotoxic to cancer cells, blocks pancreatic cancer cell growth in vivo. Int J Cancer. 2006 Oct 1;119(7):1577-85.
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